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Substance Use Disorder is a global problem that affects more than 30 million people. To date, treatment has had minimal success with a high relapse rate. CBD has recently emerged as a promising treatment for SUDs. CBD is non-rewarding, and acts on a number of receptor systems including the opioid, serotonergic, and cannabinoid systems.
“The endocannabinoid system plays an important role in common neurobiological processes underlying substance use disorder, in particular by mediating the rewarding and motivational effects of substances and substance-related cues. In turn, a number of cannabinoid drugs (e.g., rimonabant, nabiximols) have been suggested for potential pharmacological treatment for substance dependence. Recently, cannabidiol (CBD), a non-psychoactive phytocannabinoid found in the cannabis plant, has also been proposed as a potentially effective treatment for the management of substance use disorder.”
Studies suggest that these cannabinoids have the potential to reduce craving and relapse in abstinent substance users, by impairing reconsolidation of drug-reward memory, salience of drug cues, and inhibiting the reward-facilitating effect of drugs.
Click HERE to read more about the study.